The flight began with a taxiing period from the parking to the runway, which took 9 minutes and covered a distance of 2 nautical miles. The aircraft, a Boeing 737-800, then departed from runway 25 at the Falcone–Borsellino Airport, also known as LICJ. The takeoff distance was 1,496 meters, which is 50% of the runway length. The liftoff speed was 152 knots.

The local weather conditions at the time of takeoff were characterized by a temperature of 31 degrees Celsius and a wind speed of 7 knots at 39 degrees. This resulted in a crosswind of 3 knots and a tailwind of 7 knots. The aircraft then began its enroute climb, starting 1 mile northwest of Cinisi, Sicilia, Italy. The climb took 19 minutes and covered a distance of 112 nautical miles, with the aircraft ascending from an altitude of 327 meters above sea level to 10,683 meters above sea level, an increase of 10,356 meters.

After reaching the cruising altitude, the aircraft entered a level cruise phase, which lasted for 2 minutes and covered a distance of 13 nautical miles. This phase started 47 miles south of Ventotene, Lazio, Italy. The enroute descent then began 35 miles southwest of Ventotene, and the aircraft descended from 10,678 meters above sea level to 393 meters above sea level, a decrease of 10,284.3 meters, in 30 minutes and covering a distance of 102 nautical miles.

The final approach to runway 16L at the Rome–Fiumicino Leonardo da Vinci International Airport, also known as LIRF, was made from the north, with the aircraft heading 162.0 degrees at an altitude of 385.7 meters above ground level and a distance of 4 nautical miles from the runway. The landing was made on runway 16L, which has a length of 3,894 meters. The threshold height was good, but the threshold speed was slightly above the target at 146 knots.

The touchdown point was 262 meters beyond the touchdown zone, and the touchdown speed was 136 knots, which was a little fast. The touchdown rate was fair at -1.3 meters per second. The runway touchdown position was misaligned by 10.2 meters from the centerline. The local weather conditions at the time of landing were characterized by a temperature of 24 degrees Celsius and a wind speed of 2 knots at 60 degrees, resulting in a crosswind of 2 knots and a headwind of 0 knots.

The total landing distance was 2,376 meters, which is 61% of the runway length. The runway rollout alignment was slightly misaligned by 8.9 meters from the centerline. The taxiing period from the runway to the parking took 7 minutes and covered a distance of 1 nautical mile. The total flight distance was 237 nautical miles, and the flight duration was 69 minutes. The aircraft used 2,775 kilograms of fuel during the flight.