Sir Seretse Khama International Airport, Botswana, served as the departure point for the Boeing 737‑600, which taxiing from the parking to runway 08 required 3 minutes and covered less than 1 nm. The aircraft rolled out on runway 08, a takeoff distance of 1,894 m representing 47 % of the available runway, and achieved liftoff at 134 kt. Local conditions were 12 °C with a 2 kt wind from 42°, providing a 1 kt headwind and no crosswind. Immediately after departure, the climb commenced over Gaborone, ascending from 4,268 ft to 40,996 ft in 46 minutes while covering 386 nm, an increase of 36,728 ft. The aircraft entered cruise 13 miles southwest of FVZC Zisco Airport, maintaining level flight for 93 minutes over 726 nm. Descent began 18 miles southeast of HTNK Luhanyando Airport, dropping from 40,880 ft to 2,469 ft in 26 minutes across 194 nm, a decrease of 38,412 ft. A brief cruise segment of 2 minutes covered 7 nm 11 miles south of Kisarawe, followed by a descent 6 miles south of Kisarawe from 2,298 ft to 1,472 ft in 2 minutes over 6 nm, a reduction of 826 ft.

The final approach to runway 05 at HTDA Julius Nyerere International Airport began from the southwest, heading 44.0° at 4 nm and 1,291 ft AGL. Landing occurred on runway 05, 3,154 m in length, with a threshold speed well above target at 129 kt. The touchdown point was 106 m beyond the touchdown zone, with a touchdown speed of 119 kt and a touchdown rate of –150 fpm. The runway touchdown position was slightly misaligned by 3.4 m from the centreline. Local weather at the destination was 31 °C, with a 4 kt wind from 140°, providing a 3 kt crosswind and no headwind. The total landing distance was 1,192 m, 38 % of the runway, and the runway rollout alignment was very good.

After touchdown, taxiing back to the parking required 2 minutes and covered less than 1 nm. The entire flight covered a total distance of 1,326 nm over 175 minutes, consuming 7,023 kg of fuel.